文章题目：Visible Light-Induced 1,2-Diphenyldisulfane-Mediated Defluoroborylation of Polyfluoroarenes

作者：Qiao-Jing Pan1 , Yu-Qi Miao1 , Hou-Ji Cao1 , Zhenxing Liu2*, Xuenian Chen1,2*

 

摘要：A green and practical protocol of defluoroborylationof polyfluoroarenes with stable and readily accessible NHC-boranewas developed, using 1,2-diphenyldisulfane as a hydrogen atomtransfer (HAT) and single electron transfer (SET) reagentprecursor under visible-light irradiation, leading to the conciseformation of value-added fluorinated organoboron scaffolds.Mechanism studies revealed the method underwent a boryl radical addition reaction with polyfluoroarene, followed by successivesingle electron transfer pathways and defluorination of the C−F bond to offer the targeted product. This unprecedented platformrelies on 1,2-diphenyldisulfane and base without using expensive photocatalysts, highlighting the methodology has promisingapplication value to prepare borylated polyfluoroarene compounds.

 

文章信息：J. Org. Chem. 2024, 89, 5049−5059

 

文章链接：https://pubs.acs.org/doi/10.1021/acs.joc.4c00286?ref=PDF